Mohammad Azizkhani; Fereshteh Ghorat; Sayed Mohammad Ali Soroushzadeh; Mehrdad Karimi; Saeed Yekaninejad
Volume 20, Issue 7 , 2018, Pages 1-10
Abstract
Context: Neck pain is a prevalent complaint. Several clinical trial studies were conducted to evaluate the effects of cupping therapy on neck pain. The objective of this study was to assess the evidence for the effectiveness of cupping therapy as an intervention to conservative management of neck pain. ...
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Context: Neck pain is a prevalent complaint. Several clinical trial studies were conducted to evaluate the effects of cupping therapy on neck pain. The objective of this study was to assess the evidence for the effectiveness of cupping therapy as an intervention to conservative management of neck pain. Evidence Acquisition: We performed a systematic search in PubMed, Ovid, MEDLINE, CINAHL, EMBASE, Cochrane Library, a web of science, and Iranian medical databases through March 2017 without time restrictions. All clinical trials were done on non- specificneck pain, where at least one of the therapies assessed pertains to cupping therapy, were included in the study. Outcomes were pain intensity (e.g., Visual Analogue Scale, VAS), disability (e.g., Neck Disability Index, NDI), quality of life on the SP36 questionnaire, and other outcomes due to neck pain. A meta-analysis was performed to assess the effectiveness of cupping in managing neck pain. Results: Meta-analysis of five trials revealed significant differences in pain relief in favor of cupping therapy compared with the control group (VAS 100 cm, MD, -0.84 (-1.22, -0.46), I2 = 54.7%). Furthermore, a meta-analysis of six studies revealed that cuppingtherapy was clinically superior to the control group in patients with neck pain (SMD = -0.60 (-0.86, -0.35), I2 = 16.4%). Assessment of quality of life using the SP36 questionnaire showed that cupping therapy increased the quality of life in patients with neck pain compared with the control group (SMD = -0.56 (-0.20, -0.92), I2 = 51.4%).Conclusions: This study provides some evidence that cupping therapy may improve treatment of patients with neck pain.
Mohammad Azizkhani; Marzieh Vahid Dastjerdi; Maliheh Tabaraee Arani; Reyhaneh Pirjani; Mahdi Sepidarkish; Fereshteh Ghorat; Mehrdad Karimi
Volume 20, Issue 1 , 2018, Pages 1-8
Abstract
Background: Dry cupping has been used as a treatment for abnormal uterine bleeding in Iranian traditional medicine.Objectives: The present study aimed at evaluating the usefulness of dry cupping on excessive menstrual blood loss in menorrhagia with a well- validated menstrual pictogram compared to medroxyprogesterone ...
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Background: Dry cupping has been used as a treatment for abnormal uterine bleeding in Iranian traditional medicine.Objectives: The present study aimed at evaluating the usefulness of dry cupping on excessive menstrual blood loss in menorrhagia with a well- validated menstrual pictogram compared to medroxyprogesterone acetate.Methods: A total of 162 women with menorrhagia were enrolled in this prospective, randomized, controlled trial in Iran from 2015 to 2016. Written informed consent was obtained, then, patients were randomly allocated into dry cupping (three sessions of in- terrupted and kinetic dry cupping during menstrual bleeding) or medroxyprogesterone acetate (10 mg/day throughout the luteal period) groups using a random number sequence. The number of bleeding days and objective estimation of menstrual blood loss using a pictorial blood loss assessment chart (PBAC) were recorded before the intervention and at specific intervals (one and 3- months post-intervention).Results: At one and 3-months, PBAC scores were significantly lower in women treated with cupping compared with women treated with medroxyprogesterone acetate. These reductions in PBAC score were 214.9 mL with 95% CI (120.5 to 309.2) greater than medrox- yprogesterone acetate at one month and 237.3 with 95% CI (143.0 to 331.7) at 3- month follow- up period. Reduction in the number of bleeding days in the cupping group for almost one day was better than the control groups at one and 3-months follow- up (Mean difference:-1.03, 95% CI (-1.78 to -0.26), P = 0.007).Conclusions: Dry cupping is an effective treatment in reducing the intensity of bleeding during the menstrual period compared to medroxyprogesterone acetate.
Mehdi Salehi; Mohammad Azizkhani; Masumeh Mobli; Ramin Shakeri; Mehdi Saberi-Firoozi; Roja Rahimi; Mehrdad Karimi
Volume 19, Issue 7 , July 2017, , Pages 1-8
Abstract
Background: Gastroesophageal reflux disease (GERD) is one of the most prevalent digestive diseases. Long-term treatment and recurrence of symptoms after discontinuation of medication are amongst its problems.Objectives: The aim of this study is to investigate the impact of myrtle fruit syrup on the recurrence ...
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Background: Gastroesophageal reflux disease (GERD) is one of the most prevalent digestive diseases. Long-term treatment and recurrence of symptoms after discontinuation of medication are amongst its problems.Objectives: The aim of this study is to investigate the impact of myrtle fruit syrup on the recurrence of symptoms in reflux patients after the discontinuance of using a PPI.Methods: This research is a double-blind, randomized clinical study. With regard to withdrawal rate, 45 patients were selected for each group. The trial was conducted at the traditional medicine clinic at tehran university of Medical Sciences, Tehran- Iran, between November 2014 and March 2016. Diagnosis was conducted on the basis of the Mayo clinic standardized questionnaire. Every individual with heartburn or regurgitation symptoms with frequency of at least once a week was diagnosed as suffering from reflux. Omeprazole 20 mg with fasting as well as myrtle or placebo syrup 5 mL after meal were prescribed. Treatment duration was 6 weeks, after which the medicine was discontinued and patients were evaluated for 2 weeks. The cases in which recurrence of symptoms up to 14 days did not occur were considered as being non-recurrence.Results: Eighty nine people with symptoms of reflux were studied. The recurrence of symptoms was 22 people in treatment group and 27 people in control group with no significant difference (P value = 0.179). Time delay in the onset of symptoms was 9.57 days in treatment group and 6.27 days in control group which had significant difference (P value = 0.027).Conclusions: Although the recurrence of symptoms was lower in the treatment group than in the control group, there was no significant difference. However, treatment significantly delayed the onset of symptoms in quantitative terms. The findings show that further research should be implemented.
Fereshteh Ghorat; Mohammad Azizkhani; Shahriar Naji; Ali Ghorbani Ranjbary; Farzad Doostishoar
Volume 19, Issue 1 , January 2017, , Pages 1-6
Abstract
Background: Wound healing is a process that occurs following skin lesions. Shortening healing time is of critical importance as it reduces the risk of infection, complications, and costs.Objectives: In this experimental study, 36 male Wistar rats each weighting approximately 200 - 220 g were studied ...
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Background: Wound healing is a process that occurs following skin lesions. Shortening healing time is of critical importance as it reduces the risk of infection, complications, and costs.Objectives: In this experimental study, 36 male Wistar rats each weighting approximately 200 - 220 g were studied in six groups, each with 6 animals for 21 days. Hydroalcoholic extract of Burdock root was prepared through the maceration method. The animals underwent a 2 × 2 cm diameter resection of cutaneous fragment on the dorsum. The first group was kept without treatment as the control group, the second group (negative control) was treated with Eucerin, and the third group (positive control) was treated with ointment of phenytoin (1%). Eucerin based-ointments from hydroalcoholic extracts of Burdock root with concentrations of 20%, 40% and 60% of weight/weight were administered to the animals in the other three groups twice a day. The lesion diameter and programmed euthanasia were analyzed through a surgical specimen resected for histopathology.Results: The healing process was completed in 21 days in both no treatment and Eucerin groups. In the phenytoin 1% group, the healing time was 16 days and in hydroalcoholic extracts of Burdock root groups of 20%, 40% and 60%, complete wound closure was observed in 16, 16 and 14 days, respectively. All the treated groups and the control group showed significant differences when compared with the negative control and control group (P < 0.05). In addition, the histological study of the group treated with hydroalcoholic extracts of Burdock root showed that symptoms and improvement of skin tissues had a better status.Conclusions: The crude hydroalcoholic extract of Burdock root was found to cause better outcomes in the healing process, acute inflammation, and fibrosis on the 7th, 14th, and 21st day postoperatively.
